MAKING ANIMALS ALCOHOLIC: SHIFTING LABORATORY MODELS OF ADDICTION
نویسندگان
چکیده
منابع مشابه
Making Animals Alcoholic: Shifting Laboratory Models of Addiction
The use of animals as experimental organisms has been critical to the development of addiction research from the nineteenth century. They have been used as a means of generating reliable data regarding the processes of addiction that was not available from the study of human subjects. Their use, however, has been far from straightforward. Through focusing on the study of alcoholism, where the n...
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For much of the twentieth century, theories of addictive behavior and motivation were polarized between two models. The first model viewed addiction as a moral failure for which addicts are rightly held responsible and judged accordingly. The second model, in contrast, viewed addiction as a specific brain disease caused by neurobiological adaptations occurring in response to chronic drug or alc...
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In recent years, animal models in psychiatric research have been criticized for their limited translational value to the clinical situation. Failures in clinical trials have thus often been attributed to the lack of predictive power of preclinical animal models. Here, I argue that animal models of voluntary drug intake-under nonoperant and operant conditions-and addiction models based on the Di...
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red: morph-specific contest success and survival rates in a colour polymorphic agamid lizard. Animal Behaviour 74:337-341. in females is also lateralized: left-eye bias during aggressive courtship rejection in lizards. Assessment in contests of male lizards (Anolis carolinensis): how should smaller males respond when size matters? Animal Behaviour 69:1325-1336.
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To determine the neuropharmacological activity of the leaf extract of Croton zambesicus in mice and chicks. The effect of aqueous leaf extract of Croton zambesicus on thiopental sodium – induced sleeping time in mice, on gross locomotor activity (GLA) in 2-day old chicks and effect of extract on apomorphine - induced stereotyped behavior in chicks were evaluated. The a...
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ژورنال
عنوان ژورنال: Journal of the History of the Behavioral Sciences
سال: 2015
ISSN: 0022-5061,1520-6696
DOI: 10.1002/jhbs.21715